Veds Varicose Veins. Andrews, MD, FACP, Chief Medical Officer of Acer Therapeutics disc

Andrews, MD, FACP, Chief Medical Officer of Acer Therapeutics discusses his company's focus on Vascular Ehlers-Danlos Syndrome (vEDS), an inherited connective tissue disorder that is caused by defects in a protein called collagen. Tendon and muscle rupture Keratoconus 11. Individuals may also experience early-onset varicose veins, frequent nosebleeds, or bleeding that is difficult to control. The syndrome results in aortic and arterial aneurysms and dissections at a young age. This can be done by talking to your GP and/or specialist, who will then set up a referral to the closest genetic specialist to you. If you elevate your feet, the problem gets worse. I started googeling about my very visible chest veins and the first thing that popped up was veds. Richard Alexander explains how to tell when varicose veins are just cosmetic or need medical intervention and when surgery may be best. Unlike other subtypes of EDS, people with vEDS often do not have the Oct 11, 2025 · Learn the key differences between varicose veins and venous insufficiency, two common vein conditions that affect circulation and leg health. Explore the features of vEDS by selecting different body parts from the menu on the left. While vEDS can be inherited, the absence of a family history should not exclude vEDS as a possible diagnosis. Feb 11, 2025 · This session provides clear, expert-backed information for patients with Vascular Ehlers-Danlos Syndrome (vEDS), their families, and caregivers on how varicose veins develop, the risks they pose, and the safest ways to manage them. But if you’re experiencing pain, bleeding, swelling or discoloration, they might be an issue. Discover its signs, causes, diagnosis, management, and how to thrive with vEDS. What are contraindications for massage in patients with varicose veins? Deep techniques over visible varicosities, local massage if painful/sensitive varicosities are present, and massage post saline injection. We would like to show you a description here but the site won’t allow us. Our skilled pediatric heart surgeons are sometimes the only ones in the world who can perform a complex heart Carotid-Cavernous Sinus Fistula formation Thin, 'translucent' skin with visibile veins History of tendon or muscle rupture Varicose veins before age 30 (with no history of pregnancy) Frequent bruising unrelated to trauma Frequent bruising in unusual sites (examples: cheeks, back) Hypermobility of small joints Please see page 9 for surgical recommendations. mortem, that 53% underscoring of these teens the at mutations Confirmation mutations to identify having are linked a mutation of detection the diagnosis the longest to variable survivability. I have hEDS, but appear to have varicose veins on the inner part of my right thigh, near my knee joint. The condition is characterized by visible bulging veins and may be accompanied by discomfort or pain. Apr 26, 2018 · INTRODUCTION Ehlers-Danlos syndrome is a heterogeneous group of rare connective tissue disorders that often manifest with increased skin elasticity, joint hypermobility, and tissue fragility. Vascular Ehlers-Danlos syndrome (vEDS) accounts for fewer than 5% of all Ehlers-Danlos cases 1. Dec 6, 2024 · So for anybody searching the web about visible veins: They might just be visible veins! Hearing about vEDS is scary, but don’t let your health anxiety dictate your life. Varicose veins are swollen, twisted veins that you can see just under the skin's surface. Vascular Ehlers Danlos syndrome (vEDS) is a rare disorder, estimated to affect between 1 in 50,000 and 1 in 200,000 people. These include vascular events, described in detail below, and rupture of hollow organs such as bowel and the uterus (in pregnant women). I have attached photos for reference! We would like to show you a description here but the site won’t allow us. Early onset of varicose veins Arterial rupture may be preceded by aneurysm, arteriovenous fistulae (abnormal communication between an artery and a vein) or dissection, or may occur spontaneously. When you receive a new diagnosis, this can be a time of great stress, anxiety and confusion. In general, there are two types of blood vessels in the body that are part of the vascular system: arteries and veins. Arter. Learn about Vascular Ehlers-Danlos Syndrome (vEDS), a rare genetic disorder affecting blood vessels. Symptoms of potential vascular disease in the feet include: Pain when walking or exercising. vEDS can mimic other CTDs, so a connective tissue panel, cardiac panel or aortopathy panel may be ordered by a geneticist to make a proper diagnosis. Vascular Ehlers-Danlos Syndrome (vEDS) Vascular Ehlers-Danlos Syndrome (vEDS, previously known as EDS Type IV or EDS IV) is a subtype of Ehlers-Danlos Syndrome (EDS), a disorder of collagen production. 19 hours ago · Varicose veins can bleed seriously due to high pressure. Vascular Ehlers-Danlos syndrome is the most severe form of EDS with symptoms that can be life-threatening. Pointing and thinning of the cornea (the transparent front of the eye) A characteristic facial appearance with small or absent earlobes, thin nose and lips and large eyes. Find out about the symptoms, causes and treatments. Oct 11, 2025 · Life with VEDS People with VEDS are born with it, but features of the condition are not always present right away. May 4, 2023 · Several types of doctors can treat varicose veins. "Varicose veins are superficial veins you see on your legs. 3 days ago · Overview of Varicose Veins Definition and Characteristics Varicose veins are enlarged, twisted veins that often appear blue or dark purple due to pooled blood. Diagnosis is confirmed with molecular testing via Varicose veins (VVs) are common, but in Vascular Ehlers-Danlos Syndrome (vEDS), they can be more than just a cosmetic concern. High blood pressure (hypertension) and problems with heart valves (such as mitral valve prolapse) happen very frequently. It's estimated to impact 1 in 90,000 people. Learn which ingredients to look for, optimal dosages, and tips for integrating these nutrients into your… Epidemiology Varicose veins are more common in women than men and are more common in the lower limb than in the upper limb 5. Organ problems: Rupture of hollow organs like the stomach, intestines, and bladder can occur. However, venous disease continues to be an under-described component, leading to poorly-defined incidence and management. 1A review of these case records was then performed to select individuals with vEDS based on the documentations in the medical records by providers caring for the patients. Varicose veins and obesity Obesity is a major factor in developing varicose veins because it puts more weight on your legs, adding stress to the veins. Advanced diagnosis. Sep 25, 2024 · Hi all, I am very scared of possibly having veds. Mar 23, 2021 · Tendon/muscle rupture Early onset varicose veins (under the age of 30) Some people with VEDS can present without any of the external features on exam and the only findings that suggest the presence of VEDS may be multiple aneurysms and dissections in the arteries as seen by Computed tomography (CT) or magnetic resonance imaging (MRA) Mar 23, 2021 · Tendon/muscle rupture Early onset varicose veins (under the age of 30) Some people with VEDS can present without any of the external features on exam and the only findings that suggest the presence of VEDS may be multiple aneurysms and dissections in the arteries as seen by Computed tomography (CT) or magnetic resonance imaging (MRA) Jan 13, 2026 · Varicose veins directly behind the knee, or increased pressure in the kneecap region, can cause localized pain easily mistaken for joint pain. Oct 27, 2024 · How is vEDS Diagnosed? Genetic Testing for vEDS Genetic testing is used to diagnose vEDS. Ignoring leg pain or swelling? Learn early warning signs of varicose veins, risk factors, and when to seek treatment from experts. Feb 11, 2025 · Varicose veins are common in the general population, but for people with Vascular Ehlers-Danlos Syndrome (vEDS), they can pose additional challenges and risks. The symptoms listed here may not affect everyone with vEDS, and people with vEDS may have other symptoms that are not listed on this page. Vascular Ehlers-Danlos syndrome (vEDS) is a rare disorder and one of 13 types of Ehlers-Danlos syndrome (EDS). At Stanford Medicine Children’s Health, we collaborate closely with our renowned heart specialists at Betty Irene Moore Children’s Heart Center. 19 hours ago · Varicose veins are not blood clots, but the question highlights a common misunderstanding about vein health. They typically appear swollen and raised, have a bluish-purple or red color To facilitate early diagnosis, major and minor criteria are used to prompt further workup in patients with suspected vEDS. Learn about symptoms, diagnosis, and management at The Cardiovascular Care Group. Michael Frank, Cardiol Vascular EDS Vascular Ehlers Danlos syndrome (vEDS) is a rare disorder, estimated to affect between 1 in 50,000 and 1 in 200,000 people. Learn more! Jan 22, 2025 · What Are Varicose Veins? Before diving deeper into the benefits and limitations of compression stockings, it’s essential to grasp what varicose veins are and why they form. Mayo Clinic vascular specialists work with doctors trained in skin conditions (dermatologists), imaging (radiologists), blood vessel surgery (vascular surgeons) and other care healthcare professionals to diagnose and treat your condition. Oct 22, 2019 · How do you treat varicose veins? Treatment for varicose veins typically starts with medical management, which includes regular use of graduated compression stockings and leg elevation. Varicose veins are bulging veins that often appear in the legs because of weakened or damaged valves within their walls. Dec 20, 2017 · Is gotu kola effective for treating varicose veins? Learn more about this folk remedy from the parsley family. Procedures to treat varicose veins are often done as outpatient procedures. Vascular Ehlers Danlos syndrome, or VEDS, is caused by changes in the gene called COL3A1 that tells the body how to make collagen III. Learn about the symptoms across the body of Vascular Ehlers-Danlos syndrome. Please note that vEDS affects each person differently. Edema begins in the perimalleolar region and ascends up the leg. Is that common with… Jul 9, 2025 · Explore the physiological basis for varicose veins in individuals with Ehlers-Danlos syndromes and the unique considerations for safe and effective care. Pain when resting across the top of the foot and toes. They commonly occur in the legs and feet, where the pressure in the veins is highest. Dec 11, 2024 · What Are Varicose Veins? Varicose veins develop when the one-way valves in your veins, which help blood flow back to the heart, become damaged or weak. Unlike other EDS subtypes primarily characterized by joint hypermobility and skin elasticity, vEDS is distinguished by its impact on the vascular system, posing a significant risk of life-threatening complications. Venous thromboembolism (VTE), including a deep vein thrombosis (DVT) and pulmonary embolism (PE). Jan 27, 2022 · Learn more about vascular EDS, a type of Ehlers-Danlos syndrome that is estimated to affect one out of 50,000–200,000 individuals. Causes and Mechanisms The primary cause of Previous studies looking varicose characteristic veins, features narrow importance in vEDS of early patients come post found and management11. […] This diagnostic code includes vEDS and an addi-tional 12 subtypes of EDS. It affects the body’s connective tissues and is primarily characterized by fragile blood vessels, skin, and internal organs. Jan 12, 2026 · Early warning signs of vEDS include thin, translucent skin with visible blood vessels, excessive bruising from minor trauma, poor wound healing, and characteristic facial features such as a thin nose and large eyes. This information is intended for people who have been recently diagnosed with vascular Ehlers-Danlos syndrome (vEDS) and their friends and relatives. Premature skin ageing on the hands and feet. Contact The Cardiovascular Care Group for expert support. Varicose veins represent a chronic circulation problem called venous insufficiency, characterized by blood pooling and vein enlargement. I have hEDS and have always had prominent 'wormy' veins on my arms and then later on the fronts of my shins. Collagen is the main protein in connective tissue such as skin, bones, blood vessels, and many other organs and tissues. It is a rare condition with an estimated prevalence of 1 in 90,000; approximately 750 people in the UK have vEDS, and therefore many health professionals will never have encountered someone with this condition. Individuals with the other 12 forms of EDS were excluded. Understanding Vascular Ehlers-Danlos Syndrome (VEDS), a rare genetic disorder affecting collagen production, requires multidisciplinary management for optimal outcomes. It is caused by a gene mutation affecting a major protein, which causes weakness in vessel walls and hollow organs. Vascular Ehlers-Danlos syndrome (VEDS) is a genetic condition that makes the arteries and hollow organs prone to tear, due to a mutation in the COL3A1 gene. Early onset varicose veins (under the age of 30) A family history of the disorder, arterial rupture or dissection in individuals under 40 years of age, unexplained colon rupture, or spontaneous pneumothorax in the presence of other features consistent with VEDS should all lead to diagnostic studies to determine if the individual has VEDS. However, LDS patients may have hypertelerism, abnormal uvula, arterial tortu-osity and bluish sclera. This venous discomfort is often relieved by elevating the legs, which helps drain pooled blood and reduce internal venous pressure. Wound healing may be delayed and may result in widened, papyraceous scars, particularly over prominent bony pressure points (knee). Causes of varicose veins 1 day ago · Dr. Join Dr. Fragile blood vessels mean that even small changes in vein structure can lead to vein rupture, and hemosiderin deposits, making proper management essential. This allows blood to pool in the vein, increasing pressure and leading to the telltale twisted, bulging appearance. Varicose Veins - Learn about the causes, symptoms, diagnosis & treatment from the Merck Manuals - Medical Consumer Version. Restless feet, restless legs and feet at night, visible varicose veins, leg swelling, feet swelling, and leg pain during exertion. Learn more! Learn about Vascular Ehlers-Danlos Syndrome (vEDS) and it's signs and symptoms. This rare disease suffers from lack of recognition since the main clinical diagnostic criteria for vEDS are nonspecific (hematomas, skin transparency, arterial events) and it is their association that is suggestive. Early onset varicose veins (under the age of 30) family history of the disorder, arterial rupture or dissection in individuals less than 40 years of age, unexplained colon rupture, or spontaneous pneumothorax in the presence of other features consistent with VEDS should all lead to diagnostic studies to determine if the individual has VEDS. Veins are the blood vessels that return blood to the heart. Varicose veins can be difficult to live with, whether you’re self-conscious about their appearance or worried about their implications for your overall health. Sep 15, 2025 · Varicose veins or chronic venous insufficiency, sound serious, but rarely are. Ehlers-Danlos syndromes (EDS) are a group of rare inherited conditions that affect connective tissue. Mayo Clinic doctors use detailed imaging tests to diagnose varicose veins We would like to show you a description here but the site won’t allow us. It is associated with an autosomal dominant mutation in COL3A1, responsible for the synthesis of type III May 13, 2024 · Vascular Ehlers-Danlos Syndrome (VEDS) is a rare and severe form of Ehlers-Danlos Syndrome. Risk factors include: pregnancy older age female gender prolonged standing Pathology Incompetent saphenofemoral junction, which itself results from saphenofemoral valve insufficiency, is a well-known cause. NOTE: There are overlapping clinical pheno-types between VEDS and Loeys-Dietz syndrome (LDS), including the velvety and/or hyperlu-cent skin, easily visible veins, clubfoot, and dural ectasia. Sep 7, 2023 · If you have other conditions in addition to your varicose veins — like lymphedema — your massage therapist may use compression pumps and other equipment as part of a lymphatic drainage massage Find out about varicose veins, including what the symptoms are, how they're treated, causes and possible complications. It’s also more common for people with this condition to develop varicose veins at earlier ages. Early onset varicose veins The 2017 International Classification of the Ehlers–Danlos Syndromes Malfait et al, American Journal of Medical Genetics Part C (Seminars in Medical Genetics) 175C:8–26 (2017) When not treated, complications can become serious, including an enlarged aorta, aneurysms, lung collapse, early onset varicose veins, and more. Varicose veins are seen globally and influenced by activity and lifestyle. Overall, varicose veins are more common in women than men [3]. Management of vEDS Treatment and management recommendations for those with Vascular Ehlers-Danlos Syndrome, or VEDS, including circumstances to avoid and medications. vEDS is confirmed only through genetic testing. Apr 15, 2022 · In many cases, varicose veins don’t have any symptoms. People with VEDS are at high risk for severe injuries and internal bleeding. Spontaneous pneumothorax Tendon and muscle rupture Gingival recession and gingival fragility Early-onset varicose veins (under age 30 and nulliparous if female) Bowel rupture (sigmoid colon) Aneurysms, dissections, or ruptures Characteristic facial appearance “Do you sleep with your eyes open?” We would like to show you a description here but the site won’t allow us. Mar 29, 2023 · The UK National Diagnostic Service for Ehlers-Danlos Syndromes (EDS) was established in 2009 for the rare types of EDS. • Tendon and muscle rupture • Keratoconus • Gingival recession and gingival fragility • Early-onset varicose veins (under age 30 and starting prior to pregnancy if female) We CARE For What is vEDS? Tendon and muscle rupture Keratoconus Gingival recession and gingival fragility Early onset varicose veins (under age 30 and nulliparous if female) You will need to see a genetic specialist in order to determine vEDS. Typical physical signs associated with vEDS are predominantly cutaneous, as easy bruising unrelated to trauma, thin translucent skin predominantly on the upper torso and abdomen, with abnormally visible veins. Vascular Ehlers-Danlos syndrome (VEDS) is a genetic condition that is caused by a change (mutation) in the gene for collagen type 3 (the COL3A1 gene). May 22, 2020 · Confusing VEDS with more common forms of EDS is dangerous. Learn the specific first aid steps, including elevation, to manage this critical complication. Vascular Ehlers-Danlos Syndrome (vEDS) is a rare and severe subtype of Ehlers-Danlos Syndrome (EDS), a group of inherited disorders affecting connective tissue. VEDS is a lifelong disease, but the complications are often treatable. The pathophysiology, risk factors, signs/symptoms, labs, di Mar 8, 2019 · Varicose veins (varicoses or varicosities) occur when your veins become enlarged, dilated, and overfilled with blood. May 13, 2025 · This diagnosis was first identified in the father of our patient, who suffered an intestinal arterial rupture at age 16 years, had previous joint dislocations (thumb and shoulder), and early-onset varicose veins (figure), which prompted the genetic testing in the two children when they were young to screen for vEDS. If conservative measures don’t work, some patients require procedures to resolve their symptoms. 55 votes, 30 comments. Apr 10, 2022 · Vascular EDS causes people to bruise more easily. Feb 6, 2024 · Varicose vein care at Mayo Clinic Your Mayo Clinic care team. Varicose veins developing at a younger age than usual Facial features, including a thin nose and lips, large eyes, small earlobes and fine hair Gum problems, such as bleeding or receding gums Spontaneous pneumothorax (collapsed lung) Premature ageing of the skin on hands and feet Sleeping with the eyes open or partially open Feb 6, 2024 · Treatment for varicose veins may include self-care measures, compression stockings, and surgeries or procedures. They're often blue or dark purple and usually appear on your legs. Our approach to Vascular Ehlers-Danlos syndrome (VEDS) Children with vascular Ehlers-Danlos syndrome often struggle with heart problems. Hypermobile fingers and toes. Are you struggling with varicose veins, spider veins, or poor circulation? If you’re looking for vein treatment near me, we offer advanced vein therapy in The Woodlands to improve both the appearance and health of your legs. Symptoms Symptoms and signs of CVI include hyperpigmentation, stasis dermatitis, pain, cramping, chronic edema and venous ulcers. Nov 6, 2023 · The VA provides disability benefits for depression. May 22, 2025 · Discover how supplements including horse chestnut extract and vitamin C can help strengthen vein walls and alleviate symptoms of varicose veins. Fine, thinning hair. Vascular Ehlers-Danlos (vEDS) impacts arteries and internal organs making them extremely fragile. It is crucial for medical professionals caring for someone with VEDS to know these differences. Some people have signs of VEDS at birth or as young children – including conditions like congenital clubfoot, hip dislocation, limb deformity and visible veins. Varicose veins are large, dilated veins, while spider veins are chronically dilated superficial capillaries causing no harm. Learn about causes, symptoms, risks and treatment options. Dec 11, 2018 · William T. Arteries carry blood away from May 17, 2024 · Understanding Vascular Ehlers-Danlos Syndrome (VEDS), a rare genetic disorder affecting collagen production in the body. Early-onset varicose veins are one of the minor criteria used in diagnosis of vEDS. Vascular EDS (vEDS) is an inherited connective tissue disorder caused by Early onset varicose veins (under the age of 30) family history of the disorder, arterial rupture or dissection in individuals less than 40 years of age, unexplained colon rupture, or spontaneous pneumothorax in the presence of other features consistent with vEDS should all lead to diagnostic studies to determine if the individual has vEDS. Aug 23, 2017 · Having prominent veins is not exclusive to vEDS, but certainly the degree of prominence and the visible spread pattern in vEDS patients is quite amazing. This medically reviewed guide explains how valve failure in the veins leads to symptoms like leg swelling, pain,… First Responders Quick Guide Vascular EDS is a rare, life threatening condition that causes fragile tissues and presents with arterial dissection or rupture, bowel rupture, and uterine rupture at the end of pregnancy. When choosing a doctor, you'll want to consider a few key things. Oct 8, 2024 · Other features of vEDS include: Early varicose veins. Navigate the body map to learn more about the condition. Mar 23, 2023 · What is it? Varicose veins occur when veins just below the skin's surface are damaged, become swollen and fill with too much blood. While there is no VA rating for obesity, there are related disabilities that may connect weight and varicose veins to a military condition. Gingival recession and gingival Fragility 12.

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